Dengue virus Dengue virus is flavivirus genus from flaviviridae family. This virus is a RNA virus ecosahedral shaped, have infectious Envelope vertebrata including human intermediaries with mosquito and can result in fatal .
There are four serotipe of dengue virus antigenic , the DEN-1, DEN-2, DEN-3 and DEN-4. DEN-1 strain is the most frequently isolated from all isolat. Each strain has power of virulence. Therefore its difficult to be distinguished between the strain is only based on clinical symptoms and patologis but can be distinguished with neutralisation using monoclonal antibody tests and Polymerase Chain Reaction.
Rod-shaped virus of dengue, are termolabil, sensitive to be inactivated by dietileter and natrium dioxsicolat, stable at temperature of 70 C ¬ 0 C. Virion structure consists of 3 protein; Capsid, Membrane, and Envelope, 7, and protein is unstructured (NS) with a known abbreviation NS1, NS2A, NS2B, NS3, NS4A, NS4B, and NS5.
There are four serotipe of dengue virus antigenic , the DEN-1, DEN-2, DEN-3 and DEN-4. DEN-1 strain is the most frequently isolated from all isolat. Each strain has power of virulence. Therefore its difficult to be distinguished between the strain is only based on clinical symptoms and patologis but can be distinguished with neutralisation using monoclonal antibody tests and Polymerase Chain Reaction.
Rod-shaped virus of dengue, are termolabil, sensitive to be inactivated by dietileter and natrium dioxsicolat, stable at temperature of 70 C ¬ 0 C. Virion structure consists of 3 protein; Capsid, Membrane, and Envelope, 7, and protein is unstructured (NS) with a known abbreviation NS1, NS2A, NS2B, NS3, NS4A, NS4B, and NS5.
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